Spyre Therapeutics (SYRE) - Market capitalization

Market cap: HK$19.93 Billion

As of December 2025 Spyre Therapeutics has a market cap of HK$19.93 Billion. This makes Spyre Therapeutics the world's 4247th most valuable company by market cap according to our data. The market capitalization, commonly called market cap, is the total market value of a publicly traded company's outstanding shares and is commonly used to measure how much a company is worth.

Market cap history of Spyre Therapeutics from 2016 to 2025

End of year Market Cap

Year	Marketcap	Change
2025	HK$19.93 B	81.45%
2024	HK$10.98 B	81.5%
2023	HK$6.05 B	2699.95%
2022	HK$0.21 B	-88.17%
2021	HK$1.82 B	-37.52%
2020	HK$2.92 B	69.08%
2019	HK$1.73 B	22.22%
2018	HK$1.41 B	101.26%
2017	HK$0.70 B	55.28%
2016	HK$0.45 B

What is the market capitalization of a company?

The market capitalization sometimes referred as Marketcap, is the value of a publicly listed company.
In most cases it can be easily calculated by multiplying the share price with the amount of outstanding shares.

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Market capitalization of Spyre Therapeutics (SYRE)

Market cap: HK$19.93 Billion