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10,639
total market cap:
HK$1052.694 T
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Watchlist
Account
ALPS Medical Breakthroughs ETF
SBIO
#2395
ETF rank
HK$0.91 B
Marketcap
๐บ๐ธ US
Market
HK$398.83
Share price
0.31%
Change (1 day)
48.30%
Change (1 year)
๐ก Innovation ETFs
๐งฌ Biotech ETFs
Categories
Market cap
Price history
Shares outstanding
Cost to borrow
Premium/Discount
Fees (Expense ratio)
Holdings
More
Cost to borrow
Premium/Discount
Fees (Expense ratio)
Distributions
ALPS Medical Breakthroughs ETF - Holdings
Etf holdings as of
December 11, 2025
Number of holdings:
102
Full holdings list
Weight %
Name
Ticker
ISIN
Shares Held
4.42%
Avidity Biosciences Inc.
RNA
US05370A1088
72624
4.04%
Arrowhead Pharmaceuticals Inc.
ARWR
US04280A1007
67172
3.40%
Rhythm Pharmaceuticals Inc.
RYTM
US76243J1051
33981
3.18%
Axsome Therapeutics Inc.
AXSM
US05464T1043
25143
3.01%
Cytokinetics Inc.
CYTK
US23282W6057
58303
2.98%
Merus NV
MRUS
NL0011606264
36321
2.88%
Krystal Biotech Inc.
KRYS
US5011471027
13742
2.86%
Nuvalent Inc.
NUVL
US6707031075
31815
2.45%
Praxis Precision Medicines Inc.
PRAX
US74006W2070
10776
2.43%
PTC Therapeutics Inc.
PTCT
US69366J2006
37954
2.38%
Vaxcyte Inc.
PCVX
US92243G1085
62735
2.36%
Protagonist Therapeutics Inc.
PTGX
US74366E1029
30072
2.05%
Crinetics Pharmaceuticals Inc.
CRNX
US22663K1079
48838
1.99%
Alkermes PLC
ALKS
IE00B56GVS15
80101
1.88%
ACADIA Pharmaceuticals Inc.
ACAD
US0042251084
82897
1.79%
Viking Therapeutics Inc.
VKTX
US92686J1060
56468
1.77%
Celcuity Inc.
CELC
US15102K1007
20644
1.76%
Terns Pharmaceuticals Inc.
TERN
US8808811074
43869
1.75%
Newamsterdam Pharma Co. NV
NAMS
NL00150012L7
56900
1.65%
Structure Therapeutics Inc.
GPCR
US86366E1064
28748
1.60%
Arcellx Inc.
ACLX
US03940C1009
25970
1.54%
Tarsus Pharmaceuticals Inc.
TARS
US87650L1035
22117
1.51%
Apogee Therapeutics Inc.
APGE
US03770N1019
23138
1.45%
Travere Therapeutics Inc.
TVTX
US89422G1076
48658
1.42%
Xenon Pharmaceuticals Inc.
XENE
CA98420N1050
38376
1.38%
Mirum Pharmaceuticals Inc.
MIRM
US6047491013
24723
1.37%
Disc Medicine Inc.
IRON
US2546041011
17275
1.37%
Apellis Pharmaceuticals Inc.
APLS
US03753U1060
64662
1.37%
CG oncology Inc.
CGON
US1569441009
38674
1.28%
Amicus Therapeutics Inc.
FOLD
US03152W1099
152464
1.24%
Vera Therapeutics Inc.
VERA
US92337R1014
31687
1.24%
Ideaya Biosciences Inc.
IDYA
US45166A1025
43390
1.19%
Nuvation Bio Inc.
NUVB
US67080N1019
169454
1.16%
Arcus Biosciences Inc.
RCUS
US03969F1093
54210
1.14%
Viridian Therapeutics Inc.
VRDN
US92790C1045
41152
1.07%
Denali Therapeutics Inc.
DNLI
US24823R1059
72186
1.05%
Edgewise Therapeutics Inc.
EWTX
US28036F1057
52641
0.91%
Galapagos NV
GLPG
US36315X1019
32822
0.90%
Olema Pharmaceuticals Inc.
OLMA
US68062P1066
33494
0.85%
Aurinia Pharmaceuticals Inc.
AUPH
CA05156V1022
62839
0.82%
Zai Lab Ltd.
ZLAB
US98887Q1040
54208
0.78%
Celldex Therapeutics Inc.
CLDX
US15117B2025
32826
0.78%
MannKind Corp.
MNKD
US56400P7069
157470
0.76%
Immunocore Holdings PLC
IMCR
US45258D1054
25048
0.75%
Vericel Corp.
VCEL
US92346J1088
23577
0.73%
Stoke Therapeutics Inc.
STOK
US86150R1077
25985
0.71%
Zenas Biopharma Inc.
ZBIO
US98937L1052
20636
0.67%
Trevi Therapeutics Inc.
TRVI
US89532M1018
60045
0.67%
BioCryst Pharmaceuticals Inc.
BCRX
US09058V1035
104109
0.67%
Immunome Inc.
IMNM
US45257U1088
40394
0.66%
Agios Pharmaceuticals Inc.
AGIO
US00847X1046
28377
0.65%
Pharvaris NV
PHVS
NL00150005Y4
31684
0.62%
Upstream Bio Inc.
UPB
US91678A1079
26715
0.57%
Dianthus Therapeutics Inc.
DNTH
US2528281080
16050
0.56%
Relay Therapeutics Inc.
RLAY
US75943R1023
84867
0.53%
AnaptysBio Inc.
ANAB
US0327241065
13710
0.52%
Capricor Therapeutics Inc.
CAPR
US14070B3096
22465
0.51%
Immatics NV
IMTX
NL0015285941
59633
0.51%
Xencor Inc.
XNCR
US98401F1057
35081
0.49%
Tyra Biosciences Inc.
TYRA
US90240B1061
25396
0.49%
ARS Pharmaceuticals Inc.
SPRY
US82835W1080
51050
0.47%
Maze Therapeutics Inc.
MAZE
US5787841007
14105
0.46%
Palvella Therapeutics Inc.
PVLA
US6979471090
5644
0.44%
Novavax Inc.
NVAX
US6700024010
77976
0.43%
Bicara Therapeutics Inc.
BCAX
US0554771032
27119
0.43%
Rapport Therapeutics Inc.
RAPP
US75383L1026
17573
0.43%
UroGen Pharma Ltd.
URGN
IL0011407140
22592
0.42%
MBX Biosciences Inc.
MBX
US55287L1017
17320
0.39%
Erasca Inc.
ERAS
US29479A1088
136408
0.39%
Compass Therapeutics Inc.
CMPX
US20454B1044
85442
0.38%
Vir Biotechnology Inc.
VIR
US92764N1028
68068
0.38%
MoonLake Immunotherapeutics
MLTX
KY61559X1045
31693
0.38%
Theravance Biopharma Inc.
TBPH
KYG8807B1068
25014
0.37%
Keros Therapeutics Inc.
KROS
US4923271013
20182
0.37%
Geron Corp.
GERN
US3741631036
311479
0.36%
Day One Biopharmaceuticals Inc.
DAWN
US23954D1090
50407
0.36%
Kura Oncology Inc.
KURA
US50127T1097
40124
0.34%
Fulgent Genetics Inc.
FLGT
US3596641098
14975
0.33%
Replimune Group Inc.
REPL
US76029N1063
38850
0.31%
Gossamer Bio Inc.
GOSS
US38341P1021
102078
0.31%
Rigel Pharmaceuticals Inc.
RIGL
US7665597024
8674
0.29%
Astria Therapeutics Inc.
ATXS
US04635X1028
26508
0.27%
REGENXBIO Inc.
RGNX
US75901B1070
25014
0.27%
Compass Pathways PLC
CMPS
US20451W1018
45391
0.23%
Prothena Corp. PLC
PRTA
IE00B91XRN20
25991
0.21%
Annexon Inc.
ANNX
US03589W1027
48191
0.18%
Akebia Therapeutics Inc.
AKBA
US00972D1054
127126
0.17%
Autolus Therapeutics PLC
AUTL
US05280R1005
125498
0.16%
Vanda Pharmaceuticals Inc.
VNDA
US9216591084
28736
0.15%
Bicycle Therapeutics PLC
BCYC
US0887861088
24422
0.15%
Delcath Systems Inc.
DCTH
US24661P8077
17051
0.15%
Candel Therapeutics Inc.
CADL
US1374041093
26422
0.14%
Anavex Life Sciences Corp.
AVXL
US0327973006
39051
0.10%
Atea Pharmaceuticals Inc.
AVIR
US04683R1068
35828
0.08%
Arcturus Therapeutics Holdings Inc.
ARCT
US03969T1097
12966
0.07%
Cash and Equivalents
87099.74
0.06%
Tonix Pharmaceuticals Holding Corp.
TNXP
US8902608392
3573
0.05%
Rezolute Inc.
RZLT
US76200L3096
44126
0.00%
Novo Nordisk A/S
2600057D
1233
0.00%
AstraZeneca PLC
2334482D
36586
0.00%
Radius Health CVR
RAD-CVR
28640
0.00%
Chinook Therapeutics Inc.
1835589D
20700