Companies: 10,639     total market cap: S$175.581 T
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SPDR S&P Biotech ETF
XBI
#289
ETF rank
S$10.63 B
Marketcap
🇺🇸 US
Market
S$156.51
Share price
-1.39%
Change (1 day)
28.15%
Change (1 year)
🧬 Biotech ETFs
Categories

SPDR S&P Biotech ETF - Holdings

Etf holdings as of December 29, 2025

Number of holdings: 156

Full holdings list

Weight %NameTickerShares Held
1.47%AMICUS THERAPEUTICS INCFOLD8472141
1.42%PRAXIS PRECISION MEDICINES IPRAX382077
1.38%TRAVERE THERAPEUTICS INCTVTX2907431
1.36%BIOMARIN PHARMACEUTICAL INCBMRN1861315
1.35%EXELIXIS INCEXEL2433799
1.34%HALOZYME THERAPEUTICS INCHALO1595485
1.31%REGENERON PHARMACEUTICALSREGN137660
1.31%RHYTHM PHARMACEUTICALS INCRYTM954087
1.31%MODERNA INCMRNA3443152
1.31%ROIVANT SCIENCES LTDROIV4938528
1.31%VAXCYTE INCPCVX2298306
1.30%MADRIGAL PHARMACEUTICALS INCMDGL180919
1.29%KRYSTAL BIOTECH INCKRYS416950
1.28%PTC THERAPEUTICS INCPTCT1348944
1.27%AMGEN INCAMGN316952
1.27%INCYTE CORPINCY1050325
1.27%BRIDGEBIO PHARMA INCBBIO1374884
1.27%UNITED THERAPEUTICS CORPUTHR206171
1.26%VERTEX PHARMACEUTICALS INCVRTX224793
1.26%REVOLUTION MEDICINES INCRVMD1283505
1.26%GILEAD SCIENCES INCGILD823813
1.25%ABBVIE INCABBV443883
1.25%CYTOKINETICS INCCYTK1657243
1.24%IONIS PHARMACEUTICALS INCIONS1271179
1.23%AVIDITY BIOSCIENCES INCRNA1400973
1.23%ARROWHEAD PHARMACEUTICALS INARWR1451380
1.23%EXACT SCIENCES CORPEXAS987179
1.23%MIRUM PHARMACEUTICALS INCMIRM1253391
1.22%CIDARA THERAPEUTICS INCCDTX455169
1.22%SCHOLAR ROCK HOLDING CORPSRRK2218772
1.22%TG THERAPEUTICS INCTGTX3266553
1.22%CELCUITY INCCELC981619
1.21%BIOGEN INCBIIB562934
1.21%NATERA INCNTRA428802
1.20%ALNYLAM PHARMACEUTICALS INCALNY247148
1.19%ALKERMES PLCALKS3492547
1.18%VIKING THERAPEUTICS INCVKTX2663372
1.17%PROTAGONIST THERAPEUTICS INCPTGX1093818
1.17%ADMA BIOLOGICS INCADMA5002793
1.14%CRISPR THERAPEUTICS AGCRSP1735654
1.13%ACADIA PHARMACEUTICALS INCACAD3406661
1.13%INSMED INCINSM526486
1.13%GRAIL INCGRAL1052983
1.13%NEUROCRINE BIOSCIENCES INCNBIX642285
1.07%SUMMIT THERAPEUTICS INCSMMT4945330
1.03%BEAM THERAPEUTICS INCBEAM3038960
1.03%ARCUTIS BIOTHERAPEUTICS INCARQT2956653
0.99%KYMERA THERAPEUTICS INCKYMR1007833
0.99%MINERALYS THERAPEUTICS INCMLYS2197980
0.98%NUVALENT INC ANUVL789448
0.96%DYNE THERAPEUTICS INCDYN4017999
0.95%SOLENO THERAPEUTICS INCSLNO1642688
0.95%ARCELLX INCACLX1194484
0.94%VERA THERAPEUTICS INCVERA1474911
0.92%IDEAYA BIOSCIENCES INCIDYA2171288
0.90%APELLIS PHARMACEUTICALS INCAPLS2946211
0.89%SAREPTA THERAPEUTICS INCSRPT3337722
0.88%COGENT BIOSCIENCES INCCOGT1908894
0.88%CG ONCOLOGY INCCGON1812819
0.84%UNIQURE NVQURE2819463
0.83%RECURSION PHARMACEUTICALS ARXRX1.6560759E7
0.78%TWIST BIOSCIENCE CORPTWST1953114
0.78%CATALYST PHARMACEUTICALS INCCPRX2650175
0.77%APOGEE THERAPEUTICS INCAPGE831054
0.77%VERACYTE INCVCYT1476247
0.71%SYNDAX PHARMACEUTICALS INCSNDX2768300
0.71%IMMUNOVANT INCIMVT2262247
0.66%DENALI THERAPEUTICS INCDNLI3274587
0.66%VIRIDIAN THERAPEUTICS INCVRDN1705141
0.65%ULTRAGENYX PHARMACEUTICAL INRARE2698744
0.62%CELLDEX THERAPEUTICS INCCLDX1952562
0.62%BIOCRYST PHARMACEUTICALS INCBCRX6539305
0.61%AGIOS PHARMACEUTICALS INCAGIO1837384
0.61%STOKE THERAPEUTICS INCSTOK1541695
0.59%VERICEL CORPVCEL1292308
0.59%DYNAVAX TECHNOLOGIES CORPDVAX3143833
0.59%DISC MEDICINE INCIRON616982
0.54%MANNKIND CORPMNKD7734461
0.51%JANUX THERAPEUTICS INCJANX2995582
0.51%IMMUNOME INCIMNM1938314
0.50%BIOHAVEN LTDBHVN3577825
0.50%DIANTHUS THERAPEUTICS INCDNTH989246
0.47%ARDELYX INCARDX6670279
0.47%NOVAVAX INCNVAX5632194
0.45%ARCUS BIOSCIENCES INCRCUS1588461
0.41%TANGO THERAPEUTICS INCTNGX3873454
0.41%IOVANCE BIOTHERAPEUTICS INCIOVA1.2075901E7
0.41%INTELLIA THERAPEUTICS INCNTLA3682409
0.41%KURA ONCOLOGY INCKURA3203190
0.41%TAYSHA GENE THERAPIES INCTSHA5893650
0.39%RIGEL PHARMACEUTICALS INCRIGL736676
0.37%ANAPTYSBIO INCANAB603605
0.37%NURIX THERAPEUTICS INCNRIX1547210
0.36%CAREDX INCCDNA1557832
0.36%SPYRE THERAPEUTICS INCSYRE912964
0.36%KODIAK SCIENCES INCKOD1017415
0.35%PRECIGEN INCPGEN6396481
0.34%RELAY THERAPEUTICS INCRLAY3312007
0.33%PALVELLA THERAPEUTICS INCPVLA268918
0.31%XENCOR INCXNCR1670886
0.31%DAY ONE BIOPHARMACEUTICALS IDAWN2683912
0.30%ORIC PHARMACEUTICALS INCORIC3028693
0.29%REPLIMUNE GROUP INCREPL2408678
0.28%ARS PHARMACEUTICALS INCSPRY1975386
0.26%IMMUNITYBIO INCIBRX1.0381597E7
0.25%ORUKA THERAPEUTICS INCORKA657825
0.25%RAPT THERAPEUTICS INCRAPT563832
0.24%OLEMA PHARMACEUTICALS INCOLMA769369
0.24%CYTOMX THERAPEUTICS INCCTMX4676589
0.24%SANA BIOTECHNOLOGY INCSANA4686406
0.23%GERON CORPGERN1.4049243E7
0.23%UPSTREAM BIO INCUPB661319
0.23%EMERGENT BIOSOLUTIONS INCEBS1521655
0.23%MONTE ROSA THERAPEUTICS INCGLUE1152802
0.22%SIONNA THERAPEUTICS INCSION422040
0.22%LEXEO THERAPEUTICS INCLXEO1746299
0.21%GOSSAMER BIO INCGOSS5346975
0.21%VERASTEM INCVSTM2210831
0.21%KALVISTA PHARMACEUTICALS INCKALV1121235
0.21%BICARA THERAPEUTICS INCBCAX1022533
0.20%MYRIAD GENETICS INCMYGN2550875
0.18%IMMUNEERING CORP CLASS AIMRX2234914
0.18%REGENXBIO INCRGNX1011936
0.17%AKEBIA THERAPEUTICS INCAKBA8523446
0.17%VIR BIOTECHNOLOGY INCVIR2286549
0.16%PROTHENA CORP PLCPRTA1411206
0.16%COMPASS THERAPEUTICS INCCMPX2593880
0.15%CORVUS PHARMACEUTICALS INCCRVS1704620
0.15%INVIVYD INCIVVD4864278
0.15%ALTIMMUNE INCALT3346427
0.15%ANNEXON INCANNX2421303
0.15%ABSCI CORPABSI3501234
0.14%INHIBRX BIOSCIENCES INCINBX146704
0.13%4D MOLECULAR THERAPEUTICS INFDMT1425860
0.13%PRIME MEDICINE INCPRME3208685
0.13%CULLINAN THERAPEUTICS INCCGEM1054222
0.13%KEROS THERAPEUTICS INCKROS517563
0.13%ARRIVENT BIOPHARMA INCAVBP493586
0.12%ANAVEX LIFE SCIENCES CORPAVXL2671711
0.12%SAVARA INCSVRA1536038
0.12%ARBUTUS BIOPHARMA CORPABUS2000554
0.10%MIMEDX GROUP INCMDXG1184646
0.09%ERASCA INCERAS2239632
0.09%CONTRA METSERA INC-1530714
0.08%TYRA BIOSCIENCES INCTYRA264200
0.07%REZOLUTE INCRZLT2382819
0.05%SSI US GOV MONEY MARKET CLASS-3744825.130
0.04%IRONWOOD PHARMACEUTICALS INCIRWD1108380
0.02%CONTRA AKERO THERAPEUT-2033975
0.01%CONTRA INHIBRX INC-1645973
0.01%CONTRA MIRATI THERAPEU-1369552
0.01%US DOLLAR-827290.900
0.01%CONTRA VERVE THERAPEUT-900273
0.00%CONTRA BLUEPRINT MEDIC-756469
0.00%OMNIAB INC 12.5 EARNOUT2200963D161959
0.00%OMNIAB INC 15.00 EARNOUT2200964D161959

What is the market capitalization of a company?

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In most cases it can be easily calculated by multiplying the share price with the amount of outstanding shares.

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