Heron Therapeutics
HRTX
#8924
Rank
$0.15 B
Marketcap
$0.80
Share price
-0.54%
Change (1 day)
-61.94%
Change (1 year)

Heron Therapeutics - 10-Q quarterly report FY


Text size:
U.S. SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 10-Q


[X] Quarterly Report Under Section 13 or 15(d)
of the Securities Exchange Act of 1934

For the quarterly period ended September 30, 2006


[ ] Transition Report Pursuant to Section 13 or 15(d)
of the Securities Exchange Act of 1934

For the transition period from to
-------- --------

Commission file Number 0-16109


A.P. PHARMA, INC.
---------------------------------------------------
(Exact name of registrant as specified in its charter)


Delaware 94-2875566
- ------------------------------- ------------------------
(State or other jurisdiction of (IRS Employer
incorporation or organization) Identification No.)


123 Saginaw Drive, Redwood City, CA 94063
------------------------------------------
(Address of principal executive offices)

(650) 366-2626
----------------------------------------------------
(Registrant's telephone number, including area code)

Indicate by check mark whether the registrant (1) has filed all reports
required to be filed by Section 13 or 15 (d) of the Securities Exchange
Act of 1934 during the preceding 12 months (or for such shorter period
that the registrant was required to file such reports), and (2) has
been subject to such filing requirements for the past 90 days.
Yes X No
--- ---

Indicate by check mark whether the registrant is a large accelerated
filer, an accelerated filer, or a non-accelerated filer. See
definition of "accelerated filer and large accelerated filer" in
Rule 12b-2 of the Exchange Act.
Large accelerated filer [ ] Accelerated filer [ ]
---- ----
Non-accelerated filer [X ]
----

Indicate by check mark whether the registrant is a shell company (as
defined in Rule 12b-2 of the Exchange Act.)
Yes [ ] No [X ]
---- ----

At October 31, 2006, the number of outstanding shares of the Company's
common stock, par value $.01, was 25,423,663.
INDEX


PART I. FINANCIAL INFORMATION

ITEM 1. Financial Statements (unaudited):

Condensed Balance Sheets as of September 30, 2006
and December 31, 2005

Condensed Statements of Operations for the three
and nine months ended September 30, 2006 and 2005

Condensed Statements of Cash Flows for the nine
months ended September 30, 2006 and 2005

Notes to Condensed Financial Statements

ITEM 2. Management's Discussion and Analysis of Financial
Condition and Results of Operations

ITEM 3. Quantitative and Qualitative Disclosure About Market Risk

ITEM 4. Controls and Procedures

PART II. OTHER INFORMATION

ITEM 1A. RISK FACTORS

ITEM 6. Exhibits

Signatures
PART I.    FINANCIAL INFORMATION
---------------------
ITEM 1. Financial Statements:
---------------------

A.P. PHARMA, INC.
- -----------------
CONDENSED BALANCE SHEETS
(in thousands)
- ------------------------
<TABLE>
<CAPTION>

September 30, December 31,
2006 2005
------------- ------------
(Unaudited) (Note 1)
<S> <C> <C>
ASSETS
Current assets:
Cash and cash equivalents $ 3,769 $ 790
Marketable securities 14,304 5,019
Accounts receivable, net 75 1,519
Prepaid expenses and other 743 320
------ ------

Total current assets 18,891 7,648

Property and equipment, net 953 1,164
Other long-term assets 105 157
------ ------
Total assets $ 19,949 $ 8,969
====== ======

LIABILITIES & STOCKHOLDERS' EQUITY
Current liabilities:
Accounts payable $ 357 $ 614
Accrued clinical trial expenses 988 892
Accrued disposition costs 276 248
Other accrued expenses 799 1,012
------ ------
Total current liabilities 2,420 2,766
------ ------

Stockholders' equity:
Common stock 99,651 99,248
Accumulated deficit (82,097) (93,029)
Accumulated other comprehensive
loss (25) (16)
------ ------
Total stockholders' equity 17,529 6,203
------ ------
Total liabilities and stockholders'
equity $ 19,949 $ 8,969
====== ======
<FN>
See accompanying notes to condensed financial statements.
</FN>
</TABLE>
A.P. PHARMA, INC.
- -----------------
CONDENSED STATEMENTS OF OPERATIONS (UNAUDITED)
- ----------------------------------------------
(in thousands, except per share amounts)
- ---------------------------------------

<TABLE>
<CAPTION>

Three Months Ended Nine Months Ended
September 30, September 30,
--------------------------- -------------------------
2006 2005 2006 2005
---- ---- ---- ----
<S> <C> <C> <C> <C>

Royalties $ -- $ 1,334 $ -- $ 3,803
Contract revenue -- 3 -- 144
------ ------ ------ ------

Total revenue -- 1,337 -- 3,947

Operating expenses:
Research & development 3,118 2,306 10,443 7,205
General & administrative 830 868 2,695 2,540
------ ------ ------ ------

Total operating expenses 3,948 3,174 13,138 9,745
------ ------ ------ ------

Operating loss (3,948) (1,837) (13,138) (5,798)

Interest income, net 244 74 786 221

Gain on sale of interest in royalties -- -- 23,429 --

Other expense, net (49) (1) (53) --
------ ------ ------ ------

Income (loss) from continuing
operations (3,753) (1,764) 11,024 (5,577)

Income (loss) from discontinued
operations (64) 20 (92) (30)
------ ------ ------ ------

Net income (loss) $(3,817) $(1,744) $10,932 $(5,607)
====== ====== ====== ======

Basic earnings (loss) per share:
Income (Loss) from continuing
operations $ (0.15) $ (0.07) $ 0.44 $ (0.22)
====== ====== ====== ======
Net income (loss) $ (0.15) $ (0.07) $ 0.43 $ (0.22)
====== ====== ====== ======

Diluted earnings (loss) per share:
Income (Loss) from continuing
operations $ (0.15) $ (0.07) $ 0.43 $ (0.22)
====== ====== ====== ======
Net income (loss) $ (0.15) $ (0.07) $ 0.43 $ (0.22)
====== ====== ====== ======

Weighted average common shares
outstanding-basic 25,278 25,145 25,246 25,095
====== ====== ====== ======

Weighted average common shares
outstanding-diluted 25,278 25,145 25,435 25,095
====== ====== ====== ======

<FN>
See accompanying notes to condensed financial statements.
</FN>
</TABLE>
A.P. PHARMA, INC.
- -----------------
CONDENSED STATEMENTS OF CASH FLOWS (UNAUDITED)
- ----------------------------------------------
(in thousands)
- --------------
<TABLE>
<CAPTION>
For the Nine months ended
September 30,
-------------------------
2006 2005
---------- ----------
<S> <C> <C>
Cash flows from operating activities:
Net income (loss) $ 10,932 $(5,607)
Adjustments to reconcile net income
(loss) to net cash provided by (used
in) operating activities:
Loss from discontinued
operations 92 30
Loss on sale of marketable
securities 1 4
Depreciation and amortization 299 190
SFAS123R stock compensation expense 240 --
Stock and stock option compensation
awards to non-employees 79 89
Restricted stock awards 38 16
Amortization of premium/discount
and accretion of marketable
securities (22) 43
Changes in operating assets and
liabilities:
Accounts receivable 1,388 43
Prepaid expenses and other
current assets (423) 58
Other long-term assets 56 112
Accounts payable (257) 246
Accrued clinical trial expenses 96 (873)
Other accrued expenses (213) 203
------ ------
Net cash provided by (used in)
continuing operating activities 12,306 (5,446)

Net cash provided by (used in)
discontinued operations (11) 88

Cash flows from investing activities:
Purchases of property and equipment (88) (173)
Purchases of marketable securities (14,701) (8,113)
Maturities of marketable debt
securities 1,800 8,300
Sales of marketable securities 3,628 4,439
------ ------

Net cash provided by (used in)
investing activities (9,361) 4,453

Cash flows from financing activities:
Proceeds from the exercise of stock
options 11 22
Proceeds from issuance of shares under
Employee Stock Purchase Plan 34 53
Proceeds from issuance of restricted
stock -- 1
------ ------
Net cash provided by financing
activities 45 76

Net increase (decrease) in cash and
cash equivalents 2,979 (829)
Cash and cash equivalents, beginning
of the period 790 3,110
------ ------
Cash and cash equivalents, end
of the period $ 3,769 $ 2,281
====== ======

<FN>
See accompanying notes to condensed financial statements.
</FN>
</TABLE>
A.P. PHARMA, INC.
- -----------------
NOTES TO CONDENSED FINANCIAL STATEMENTS
- -----------------------------------
SEPTEMBER 30, 2006 and 2005 (UNAUDITED)
- ---------------------------------------

(1) Basis of Presentation
---------------------


A.P. Pharma, Inc. (the "Company", "we", "our", or "us") is a
specialty pharmaceutical company focused on the development of
ethical (prescription) pharmaceuticals utilizing its
proprietary polymer-based drug delivery systems. The Company's
primary focus is the development and commercializtion of its
bioerodible injectable and implantable systems under the trade
name Biochronomer(TM). Initial target areas of application for
the Company's drug delivery technology include anti-nausea,
pain mangagement, anti-inflammation and DNA/RNAI applications.

The accompanying unaudited condensed financial statements have
been prepared in accordance with accounting principles
generally accepted in the United States of America ("GAAP") for
interim financial information and with the instructions to Form
10-Q and Article 10 of Regulation S-X. Accordingly, they do not
include all of the information and footnotes required by GAAP
for complete financial statements. All adjustments (all of
which are of a normal recurring nature) considered necessary
for a fair presentation have been included. Operating results
for the three and nine months ended September 30, 2006 are not
indicative of the results that may be expected for the year
ending December 31, 2006 or for any other period. The
condensed balance sheet as of December 31, 2005 has been
derived from the audited financial statements as of that date
but it does not include all of the information and notes
required by GAAP. These condensed financial statements and the
notes thereto should be read in conjunction with the audited
financial statements and notes thereto included in our Annual
Report on Form 10-K for the year ended December 31, 2005 filed
with the Securities and Exchange Commission (the "SEC") on
March 31, 2006 (our "2005 10-K").

Summary of Critical Accounting Policies
- ---------------------------------------

Except for the adoption of FAS 123(R) (see Stock-Based
Compensation) there have been no significant changes in our
critical accounting policies during the nine months ended
September 30, 2006 compared to those previously disclosed in
our 2005 10-K.

Use of Estimates
- ----------------

The preparation of our financial statements in conformity with
GAAP requires management to make estimates and assumptions that
affect the amounts reported in our financial statements and
accompanying notes. Estimates were made relating to useful
lives of fixed assets, valuation allowances, impairment of
assets, accrued clinical and preclinical expenses, valuation of
stock-based compensation and contingencies. Actual results
could differ materially from those estimates.

Revenue Recognition
- -------------------

Our revenue arrangements with multiple deliverables are divided
into separate units of accounting if certain criteria are met,
including whether the delivered element has stand-alone value
to the customer and whether there is objective and reliable
evidence of the fair value of the undelivered elements. The
consideration we receive is allocated among the separate units
based on their respective fair values, and the applicable
revenue recognition criteria are considered separately for each
of the separate units. Advance payments received in excess of
amounts earned are classified as deferred revenue until earned.

* Royalties
Royalties from licensees are based on third-party sales of
licensed products or technologies and recorded as earned in
accordance with contract terms when third-party results can
be reliably determined and collectibility is reasonably
assured.

Generally, contractually required minimum royalties are
recorded ratably throughout the contractual period.
Royalties in excess of minimum royalties are recognized as
earned when the related product is shipped to the end
customer by our licensees based on information provided to
us by our licensees.

* License Fees
Licensing agreements generally provide for periodic minimum
payments, royalties, and/or non-refundable license fees.
These licensing agreements typically require a non-
refundable license fee and allow partners to sell our
proprietary products in a defined field or territory for a
defined period. License agreements provide for the Company
to earn future revenue through royalty payments. These non-
refundable license fees are initially reported as deferred
revenues and recognized as revenues over the estimated life
of the product to which they relate as we have continuing
involvement with licensees until the related product is
discontinued or the related patents expire, whichever is
earlier. License fees received in connection with
arrangements where we have no continuing involvement are
recognized as revenue when the amounts are received or when
collectibility is assured, whichever is earlier. No such
fees were recorded during the nine months ended September
30, 2006.

A milestone payment is a payment made by a third party or
corporate partner to us upon the achievement of a
predetermined milestone as defined in a legally binding
contract. Milestone payments are recognized as license fees
revenue when the milestone event has occurred and we have
completed all milestone related services such that the
milestone payment is currently due and is non-refundable.
No such fees were recorded during the nine months ended
September 30, 2006.

* Contract Revenues
Contract revenues relate to research and development
arrangements that generally provide for the Company to
invoice research and development fees based on full-time
equivalent hours for each project. Revenues from these
arrangements are recognized as the related development costs
are incurred. These revenues approximate the costs
incurred. No such revenues were recorded during the nine
months ended September 30, 2006.

Sale of Royalty Revenue
-----------------------

In January 2006, we completed the sale of our rights to
royalties on sales of Retin-A Micro(R) and Carac(R) for up to
$30 million. We received proceeds of $25 million upon the
closing of the transaction and may receive up to an additional
$5 million based on the satisfaction of certain predetermined
milestones. The royalty interest agreement was entered into by
the parties in January 2006, but the effective date of the sale
of the royalty interest was October 1, 2005. The royalties
recognized by the Company from October 1, 2005 through December
31, 2005 were accounted for as an offset against the $25
million gain.

Cash Equivalents and Short-term Investments
- -------------------------------------------

We consider all short-term investments in debt securities which
have original maturities of less than three months at date of
purchase to be cash equivalents. Investments which have
original maturities of three months or longer are classified as
marketable securities in the accompanying condensed balance
sheets. Marketable securities are classified as available for
sale at the time of purchase and carried at fair value.
Unrealized gains or losses, if any, are recorded as other
comprehensive income or loss in stockholders' equity.
Unrealized losses recorded as of September 30, 2006 were
$25,000.

Accrued Disposition Costs
- -------------------------

Costs relating to disposal of discontinued operations are
reported as accrued disposition costs in the accompanying
condensed balance sheets. Accrued disposition costs include
severance costs and gross profit guarantees.

Concentrations of Credit Risk
- -----------------------------

Financial instruments that potentially subject us to
concentrations of credit risk consist primarily of cash
equivalents and marketable securities. We invest excess cash
in a variety of high grade short-term, interest-bearing
securities. This diversification of risk is consistent with
our policy to preserve principal and to maintain liquidity. In
consequence, we do not believe concentrations of credit risk
are an issue.

Segment and Geographic Information
- ----------------------------------

Our operations are confined to a single business segment, the
design and commercialization of polymer technologies for
pharmaceutical and other applications. Substantially all of
our revenues have been derived from domestic customers.

Stock-Based Compensation
- ------------------------

Refer to Note 2 "Stock-Based Compensation" and Note 8
Stockholders' Equity in our 2005 10-K for further information
regarding our adoption of SFAS 123(R) and our stock-based
compensation arrangements, including related disclosures
required upon the adoption of SFAS 123(R). On January 1, 2006,
we adopted the provisions of Financial Accounting Standards
Board Statement No. 123R, "Share-Based Payment" (SFAS 123R).
SFAS 123R revised SFAS 123, "Accounting for Stock-Based
Compensation" and supersedes APB Opinion No. 25, "Accounting
for Stock Issued to Employees." SFAS 123R requires companies
to measure and recognize compensation expense for all employee
share-based payments at fair value over the service period
underlying the arrangement. Accordingly, we are required to
record the grant-date or purchase-date fair value of stock
options issued to employees and employee stock purchases. We
have recorded the compensation expense for stock options issued
to non-employees and restricted stock awards to employees and
directors. Compensation related to options granted to non-
employees is periodically remeasured as earned. We adopted SFAS
123R using the "modified prospective" method, whereby fair
value of all previously-granted employee share-based
arrangements remaining unvested at January 1, 2006, based on
the grant-date value estimated in accordance with the pro forma
provisions of SFAS 123, and all grants made on or after January
1, 2006, based on fair value estimated in accordance with SFAS
123(R), have been included in our determination of share-based
compensation expense for the three and nine months ended
September 30, 2006. We have not restated our operating results
for the three and nine months ended September 30, 2005 to
reflect charges for the fair value of share-based arrangements.

The fair value of each employee and director grant of options
to purchase common stock is estimated on the date of the grant
using the Black-Scholes option-pricing model with the following
weighted-average assumptions used for grants for the quarter
ended September 30, 2006: 1) risk-free interest rate of 5.01%
for stock options and 4.95% for employee stock purchase plan;
2) expected dividend yield of 0% for both stock options and
employee stock purchase plan; 3) expected holding period of
6.25 years based on the simplified method provided in Staff
Accounting Bulletin No. 107 for "plain vanilla options" and
expected term of 1.25 years for employee stock purchase plan
based on weighted-average purchase period of the plan; 4)
expected volatility of 240% for stock options and 71% for
employee stock purchase plan based on the Company's historical
stock prices; and 5) an estimated forfeiture rate of 4.2% of
the options granted based on historical data.

The SFAS 123R share-based compensation expenses recorded for
awards granted under the stock option plans and employee stock
purchase plan were approximately $74,000 and $240,000, net of
estimated forfeitures, for the three and nine months ended
September 30, 2006. The share-based compensation expense of
$99,000 and $141,000 was recorded in research and development
expense and general and administrative expense for the nine
months ended September 30, 2006, respectively. No tax benefit
was recognized related to share-based compensation expense
since we have incurred operating losses and we have established
a full valuation allowance to offset all the potential tax
benefits associated with our deferred tax assets.

During the quarter ended September 30, 2006 we did not grant
any restricted stock awards. As of September 30, 2006, we had
a total of 235,000 shares of restricted stock awards granted to
employees and directors, of which 135,000 shares have been
vested. The compensation costs charged as operating expenses
for restricted stock awards were $19,000 and $38,000 for the
three and nine months ended September 30, 2006, respectively,
and $8,000 and $16,000 for the three and nine months ended
September 30, 2005.

During the quarter ended September 30, 2006 we granted 25,000
options to directors to purchase common stock. The following
table summarizes option activity for the nine months ended
September 30, 2006:



<TABLE>
<CAPTION>
Weighted
Weighted Average
Average Remaining Aggregate
Exercise Contractual Intrinsic
Shares Price Term Value
------ -------- ----------- ---------
<S> <C> <C> <C> <C>
Outstanding at January 1, 2006 2,165,966 $3.40
Granted 214,940 $1.62
Exercised (1,797) $1.55
Expired and forfeited (11,335) $1.66
---------
Outstanding at March 31, 2006 2,367,774 $3.25 5.5 $429,453
Granted 50,000 $1.74
Exercised (1,090) $1.05
Expired and forfeited (69,421) $9.10
---------
Outstanding at June 30, 2006 2,347,263 $3.04 5.5 $239,426
Granted 25,000 $0.89
Exercised (6,719) $1.07
Expired (161,542) $5.15
Forfeited (5,448) $1.53
---------
Outstanding at September 30, 2006 2,198,554 $2.87 5.48 $ 7,285
=========
Options exercisable at
September 30, 2006 1,776,054 $3.17 4.7 $ 2,251
</TABLE>




As of September 30, 2006 there was approximately $497,741 of
total unrecognized compensation expense related to nonvested
stock options. This expense is expected to be recognized over
a weighted-average period of 1.28 years.

Prior to January 1, 2006, we accounted for employee stock-based
grants in accordance with SFAS No. 123, "Accounting for Stock-
Based Compensation," as amended by SFAS No. 148, "Accounting
for Stock-Based Compensation-Transition and Disclosure". We
have provided below the pro forma disclosures of the effect on
net loss and net loss per share as if SFAS No. 123 had been
applied in measuring compensation expense for the three and
nine months ended September 30, 2005. Dollars in thousands
except per share amounts.

<TABLE>
<CAPTION>
Three Months Nine Months
Ended Ended
September 30, September 30,
2005 2005
------------- -------------
<S> <C> <C>
Net loss, as reported $(1,744) $(5,607)
Deduct:
Stock-based employee
compensation expense
determined under FAS No. 123 (92) (251)
------ ------
Pro forma net loss $(1,836) $(5,858)
====== ======
Basic and diluted loss per
share, as reported $ (0.07) $ (0.22)
====== ======
Basic and diluted pro forma
loss per share $ (0.07) $ (0.23)
====== ======
</TABLE>

Fair values of awards granted under the stock option plans and
employee stock purchase plan were estimated at grant date using
the Black-Scholes option pricing model. For pro forma
disclosure, the estimated fair value of the options is
amortized to expense over the vesting period of the options
using the straight line method. Forfeitures have been
accounted for in the period in which they occurred. The
multiple option approach is used to value the purchase rights
granted under the employee stock purchase plan. We used the
following assumptions for the three and nine months ended
September 30, 2005:


<TABLE>
<CAPTION>
Three Months Nine Months
Ended Ended
September 30, September 30,
2005 2005
------------- -------------
<S> <C> <C>
Expected life in years (from
grant date):
Stock options 5 5
Employee stock purchase plan 1.5 - 2 1.5 - 2
Interest rate:
Stock options 4.2% 4%
Employee stock purchase plan 2.55%-3.63% 1.47%-3.63%
Volatility:
Stock options 78% 78%
Employee stock purchase plan 84%-94% 59%-94%
Expected dividend yield: 0% 0%
</TABLE>

Reclassifications
- -----------------

Certain amounts in the prior year's condensed financial
statements have been reclassified to conform with the current
presentation of the financial statements. Amortization of
premium/discount and accretion of marketable securities in the
prior year's quarter have been reclassified from investing
activities to operating activities on the condensed statements
of cash flows.

(2) Earnings (Loss) Per Share Information
-----------------------------------

Basic earnings (loss) per share is computed by dividing net
income (loss) by the weighted-average number of common shares
outstanding. Because the Company is in a net loss position for
the three months ended September 30, 2006 and 2005 and nine
months ended September 30, 2005, diluted earnings per share is
also calculated using the weighted average number of common
shares outstanding excluding the effect of options which are
antidilutive. For the nine months ended September 30, 2006,
diluted earnings per share is calculated using the weighted
average number of common shares outstanding and other dilutive
securities.

The following is a reconciliation of the numerators and
denominators of the basic and diluted earnings per share
computations (in thousands):



<TABLE>
<CAPTION>
Three Months Nine Months
Ended Ended
September 30, September 30,
------------- -------------
2006 2005 2006 2005
---- ---- ---- ----
<S> <C> <C> <C> <C>
Numerator:
Net income (loss) $(3,817) $(1,744) $10,932 $(5,607)
====== ====== ====== ======

Denominator:
Weighted-average shares
outstanding used to compute
basic earnings per share 25,278 25,145 25,246 25,095
Effect of dilutive stock options,
employee stock purchase
and restricted stock awards -- -- 189 --
------ ------ ------ ------

Weighted-average shares
outstanding and dilutive
securities used to compute
diluted earnings per share 25,278 25,145 25,435 25,095
====== ====== ====== ======
</TABLE>




(3) Comprehensive Income (Loss)
---------------------------
Comprehensive income (loss) for the three and nine months ended
September 30, 2006 and 2005 consists of the following (in
thousands):



<TABLE>
<CAPTION>
Three Months Ended Nine Months Ended
September 30, September 30,
------------------ -----------------
2006 2005 2006 2005
---- ---- ---- ----
<S> <C> <C> <C> <C>
Net income (loss) $(3,817) $(1,744) $10,932 $(5,607)

Unrealized gains (losses) on
available-for-sale marketable
securities 33 (6) (9) (3)
------ ------ ------ ------

Comprehensive income (loss) $(3,784) $(1,750) $10,923 $(5,610)
====== ====== ====== ======
</TABLE>




(4) Stockholders' Equity
--------------------

During the nine months ended September 30, 2006, 108,887 shares
of common stock were issued primarily through the exercise of
stock options, employee stock purchases, issuance of restricted
stock awards and for the payment of directors' fees.

(5) Discontinued Operations
-----------------------

We completed the sale of certain assets of our Analytical
Standards division as well as certain technology rights for our
topical pharmaceutical and cosmeceutical product lines and
other assets ("cosmeceutical and toiletry business") in
February 2003 and July 2000, respectively.

The Analytical Standards division and cosmeceutical and
toiletry business are reported as discontinued operations for
all periods presented in the accompanying condensed statements
of operations.

Income (loss) from discontinued operations represents the
income (loss) attributable to our Analytical Standards division
that was sold to GFS Chemicals on February 13, 2003, and
changes in estimates for our cosmeceutical and toiletry
business that was sold to RP Scherer on July 25, 2000, as
follows (in thousands):




<TABLE>
<CAPTION>
For the Three For the Nine
Months Ended Months Ended
September 30, September 30,
------------- -------------
2006 2005 2006 2005
---- ---- ---- ----
<S> <C> <C> <C> <C>
Analytical Standards Division
- -----------------------------
Royalties earned in excess of
minimum amount recorded $ 16 $ 29 $ 38 $ 42

Cosmeceutical and Toiletry Business
- -----------------------------------
Change in estimates for gross
profit guarantees (80) (9) (130) (72)
---- ---- ---- ----
Total loss from discontinued
operations $ (64) $ (20) $ (92) $ (30)
==== ==== ==== ====
</TABLE>



Basic and diluted earnings (loss) per common share from
discontinued operations were less than $0.01 per share for the
nine months ended September 30, 2006 and 2005, respectively.

Liabilities related to the discontinued operations at September
30, 2006 in the amount of $276,000 include severance costs and
accruals for gross profit guarantees. These liabilities are
reported as accrued disposition costs in the accompanying
condensed balance sheets.

Under the terms of the agreement with RP Scherer, we guaranteed
a minimum gross profit percentage on RP Scherer's combined
sales of products to Ortho Neutrogena and Dermik ("Gross Profit
Guaranty"). The guaranty period commenced on July 1, 2000 and
ends on the earlier of July 1, 2010 or the end of two
consecutive guaranty periods where the combined gross profit on
sales to Ortho and Dermik equals or exceeds the guaranteed
gross profit. We expect the annual Gross Profit Guaranty
payments to range from approximately $100,000 to $150,000 for
the remainder of the guaranty period. As the minimum amount of
Gross Profit Guaranty due is based on sales by RP Scherer and
can not be estimated, no accrual has been recorded relating to
sales in future periods.

Cash provided by (used in) discontinued operations primarily
relates to royalty payments received from GFS Chemicals for the
sale of certain products offset by a payment of $100,000
relating to the gross profit guaranty.

A summary of activity for liabilities related to discontinued
operations for the nine months ended September 30, 2006
follows: (in thousands)

<TABLE>
<CAPTION>
<S> <C>
Accrual at December 31, 2005 $248
Additional accrual for gross profit
guaranty 130
Payment for gross profit guaranty (100)
Payment under severance agreement (2)
---
Accrual at September 30, 2006 $276
===
</TABLE>

(6) Subsequent Event
----------------

On October 2, 2006, we announced that we had granted an
exclusive license to RHEI Pharmaceuticals to develop and sell
APF530 in Greater China which includes China, Taiwan, Hong Kong
and Macau. While specific license terms were not disclosed,
the agreement includes an upfront payment and provisions for
milestone payments and double digit percentage royalties on
future net sales. APF530 is in Phase 3 clinical trial for the
prevention of acute and delayed chemotherapy-induced nausea and
vomiting.
ITEM 2. Management's Discussion and Analysis of Financial Condition
-----------------------------------------------------------
and Results of Operations (dollars in thousands unless
------------------------------------------------------
otherwise indicated)
--------------------

FORWARD-LOOKING STATEMENTS

This Form 10-Q contains "forward-looking statements" as defined by
the Private Securities Reform Act of 1995. These forward-looking
statements involve risks and uncertainties including uncertainties
associated with timely development, approval, launch and acceptance
of new products, satisfactory completion of clinical studies,
establishment of new corporate alliances, progress in research and
development programs and other risks and uncertainties identified in
the Company's filings with the Securities and Exchange Commission.
We caution investors that forward-looking statements reflect our
analysis only on their stated date. We do not intend to update them
except as required by law.

CRITICAL ACCOUNTING POLICIES AND ESTIMATES

See Note 1 of Notes to Condensed Financial Statements. Except for
the adoption of FAS 123(R), we believe that our current critical
policies and estimates have not changed from those discussed in our
2005 10-K.

Results of Operations for the Three and Nine Months Ended September
- -------------------------------------------------------------------
30, 2006 and 2005
- -----------------

Our revenue has been derived principally from royalties and contract
revenues. Under strategic alliance arrangements entered into with
certain companies, we received non-refundable upfront fees,
milestone payments and royalties based on third party product sales.

In January 2006, we completed the sale of our rights to royalties on
sales of Retin-A Micro(R) and Carac(R) for up to $30 million. We
received proceeds of $25 million upon the closing of the transaction
and may receive up to an additional $5 million based on the
satisfaction of certain predetermined milestones. The royalty
interest agreement was entered into by the parties in January 2006,
but the effective date of the sale of the royalty interest was
October 1, 2005. The royalties recognized by the Company from
October 1, 2005 through December 31, 2005 were accounted for as an
offset against the $25 million gain. As a result of this
transaction, royalties for the third quarter of 2006 decreased to $0
from $1.3 million in the corresponding quarter of the prior year and
decreased in the first nine months of 2006 to $0 from $3.8 million
in the first nine months of 2005. We will not record additional
royalty revenue on sales of Retin-A Micro and Carac in future
periods.

Contract revenue, which is derived from work performed under
collaborative research and development arrangements, decreased from
$3 to $0 in the third quarter of 2006 and decreased from $144 to $0
in the first nine months of 2006. The amount of contract revenue
varies from period to period depending on the level of activity
requested of us by our collaborators. Therefore we cannot predict
the amount of contract revenue in future periods.

Research and development expense for the third quarter of 2006
increased by $812 from $2.3 million to $3.1 million due mainly to
expenditures in the third quarter on our Phase 3 trial program for
APF530, our product candidate for the prevention of chemotherapy-
induced nausea and vomiting. Research and development expense for
the first nine months of 2006 increased by $3.2 million from $7.2
million to $10.4 million due mainly to the preparations and
initiation of our Phase 3 trial program for APF530. We expect
research and development expense to increase in the last quarter of
2006 as we continue to conduct, at an accelerated pace, our Phase 3
trial program for APF530.

General and administrative expense decreased for the third quarter
of 2006 by $38 from $868 to $830 and increased for the first nine
months of 2006 by $155 from $2.5 million to $2.7 million due
primarily to outside consultant fees. We expect general and
administrative expense for the fourth quarter of 2006 to remain
relatively constant with the first three quarters of the year.

We expect our non-cash operating expenses for employee share-based
compensation for the fourth quarter of 2006 to remain relatively
constant with the first three quarters of the year.

Interest income, net, increased for the third quarter of 2006 by
$170 to $244 from $74 and for the first nine months of 2006 by $565
from $221 to $786 due to higher interest rates earned on higher
average cash, cash equivalents and marketable securities balances.

Loss from discontinued operations represents the net loss
attributable to the Analytical Standards division which was sold to
GFS Chemicals, Inc. in February 2003 and the cosmeceutical and
toiletries business which was sold to RP Scherer Corporation in July
2000. Net loss from discontinued operations totaled $64 for the
three months ended September 30, 2006, compared with a net loss of
$20 in the three months ended September 30, 2005. For the nine
months ended September 30, 2006, net loss from discontinued
operations increased by $61 to $91 from $30 in the year-ago period.

Capital Resources and Liquidity
- -------------------------------

Cash, cash equivalents and marketable securities increased by $12.3
million to $18.1 million at September 30, 2006 from $5.8 million at
December 31, 2005 due to the cash received from the sale of our
interest in royalties on sales of Retin-A Micro and Carac in January
2006, partially offset by cash used in operating activities.

Net cash provided by continuing operating activities for the nine
months ended September 30, 2006 was $12.3 million, compared to net
cash of $5.4 million used in continuing operating activities for the
nine months ended September 30, 2005. The increase in net cash
provided by operating activities from 2005 to 2006 was mainly due to
proceeds from the sale of our interest in royalties in January 2006.

Net cash used in investing activities for the nine months ended
September 30, 2006 was $9.4 million compared to net cash of $4.5
million provided by investing activities for the nine months ended
September 30, 2005. The increase in the cash used in investing
activities was primarily due to the purchases of $14.7 million of
marketable securities.

Our future capital requirements will depend on numerous factors
including, among others, our ability to enter into collaborative
research and development and licensing agreements; progress of
product candidates in preclinical and clinical trials; investment in
new research and development programs; time required to gain
regulatory approvals; resources that we devote to self-funded
products; potential acquisitions of technology, product candidates
or businesses; and the costs of defending or prosecuting any patent
opposition or litigation necessary to protect our proprietary
technology.

To date, we have financed our operations including technology and
product research and development, primarily through income from
collaborative research and development fees, the proceeds received
from the sale of our Analytical Standards division, the sale of our
cosmeceutical and toiletry business and the sale of our interest in
royalties on sales of Retin-A Micro(R) and Carac(R), the sale of
common stock in June 2004, and interest earned on short-term
investments. In October 2006, we granted an exclusive license to
RHEI Pharmaceuticals to develop and sell APF530 in Greater China
which includes China, Taiwan, Hong Kong and Macau. While specific
license terms were not disclosed, the agreement includes an upfront
payment and provisions for milestone payments and double digit
percentage royalties on future net sales.

We expect that existing cash, cash equivalents and marketable
securities, together with interest income, receipts from the sale of
our interest in royalties and other revenue-producing activities
including license fees will be sufficient to meet our cash needs
through the first quarter of 2007. We are actively seeking partners
in the U.S. and abroad to take over the funding of the Phase 3
clinical trial of APF530, and to commercialize the product upon
approval by the FDA. Also, we are currently investigating various
financing options to fund our continued development of APF530 and
potentially additional compounds. We may be unable to raise
sufficient additional capital when we need it or to raise capital on
favorable terms. The sale of equity or convertible debt securities
in the future may be dilutive to our stockholders, and debt
financing arrangements may require us to pledge certain assets and
enter into covenants that could restrict certain business activities
or our ability to incur further indebtedness and may contain other
terms that are not favorable to us or our stockholders. If we are
unable to obtain adequate funds on reasonable terms, we may be
required to curtail operations significantly or to obtain funds by
entering into financing, supply or collaboration agreements on
unattractive terms.

Below is a summary of fixed payments related to certain contractual
obligations (in thousands). This table excludes amounts already
recorded on our condensed balance sheet as current liabilities at
September 30, 2006.

<TABLE>
<CAPTION>
Less More
than 2 to 3 4 to 5 than
Total 1 year years years 5 years
----- ------ ------ ------ -------
<S> <C> <C> <C> <C> <C>
Operating Leases $2,367 $508 $1,053 $806 $ --
===== === ===== === ===
</TABLE>


ITEM 3. Quantitative and Qualitative Disclosure about Market Risk
----------------------------------------------------------

Since December 31, 2005, there have been no material changes in the
Company's market risk exposure.

ITEM 4. Controls and Procedures
-----------------------

Evaluation of disclosure controls and procedures: We carried out an
evaluation, under the supervision and with the participation of our
management, including the Chief Executive Officer and Chief
Financial Officer, of the effectiveness of the design and operations
of our disclosure controls and procedures pursuant to Rule 13a-15(b)
of the Exchange Act. Based upon that evaluation, the Chief
Executive Officer and Chief Financial Officer concluded that as of
September 30, 2006, the end of period covered by this report, our
disclosure controls and procedures were effective at the reasonable
assurance level to alert them in a timely manner to material
information relating to the Company required to be included in our
Exchange Act filings.

Changes in internal controls: During the three months ended
September 30, 2006, there have been no significant changes in our
internal control over financial reporting that materially affected,
or are reasonably likely to materially affect, our internal control
over financial reporting.
PART II. OTHER INFORMATION
-----------------

ITEM 1A. Risk Factors

There have been no material changes to the risk factors set forth
in the "RISK FACTORS" section of our Annual Report on Form 10-K for the
fiscal year ended December 31, 2005.

ITEM 6. Exhibits

Exhibit 10.AA License Agreement, dated as of October 1, 2006,
between A.P. Pharma, Inc. and RHEI PHARMACEUTICALS, INC. Confidential
treatment has been requested with respect to the omitted portions of
this exhibit.

Exhibit 31.1 Certification of Chief Executive Officer pursuant to
Rules 13A-14(a) Promulgated under the Securities Exchange Act of 1934
as amended.

Exhibit 31.2 Certification of Chief Financial Officer pursuant to
Rules 13A-14(a) Promulgated under the Securities Exchange Act of 1934
as amended.

Exhibit 32 Certifications of Chief Executive Officer and Chief
Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted
pursuant to Section 906 of the Sarbanes-Oxley Act of 2002.
SIGNATURES

Pursuant to the requirements of the Securities Exchange Act of 1934,
the registrant has duly caused this report to be signed on its
behalf by the undersigned thereunto duly authorized.


A.P. PHARMA, INC.



Date: November 7, 2006 By: /S/ Gregory H. Turnbull
------------------ -------------------------
Gregory H. Turnbull
President and Chief
Executive Officer



Date: November 7, 2006 By: /S/ Stephen C. Whiteford
------------------ --------------------------
Stephen C. Whiteford
Vice President, Finance and
Chief Financial Officer