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Watchlist
Account
ALPS Medical Breakthroughs ETF
SBIO
#2253
ETF rank
ยฃ78.88 M
Marketcap
๐บ๐ธ US
Market
ยฃ37.57
Share price
1.29%
Change (1 day)
28.16%
Change (1 year)
๐ก Innovation ETFs
๐งฌ Biotech ETFs
Categories
Market cap
Price history
Shares outstanding
Cost to borrow
Premium/Discount
Fees (Expense ratio)
Holdings
More
Cost to borrow
Premium/Discount
Fees (Expense ratio)
Distributions
ALPS Medical Breakthroughs ETF - Holdings
Etf holdings as of
December 3, 2025
Number of holdings:
102
Full holdings list
Weight %
Name
Ticker
ISIN
Shares Held
4.50%
Avidity Biosciences Inc.
RNA
US05370A1088
65216
3.78%
Arrowhead Pharmaceuticals Inc.
ARWR
US04280A1007
60236
3.26%
Cytokinetics Inc.
CYTK
US23282W6057
52327
3.22%
Axsome Therapeutics Inc.
AXSM
US05464T1043
22591
3.07%
Rhythm Pharmaceuticals Inc.
RYTM
US76243J1051
30477
3.02%
Merus NV
MRUS
NL0011606264
32617
2.94%
Nuvalent Inc.
NUVL
US6707031075
28495
2.59%
Krystal Biotech Inc.
KRYS
US5011471027
12366
2.59%
Vaxcyte Inc.
PCVX
US92243G1085
56275
2.49%
PTC Therapeutics Inc.
PTCT
US69366J2006
34114
2.24%
Protagonist Therapeutics Inc.
PTGX
US74366E1029
27004
2.05%
Alkermes PLC
ALKS
IE00B56GVS15
71953
1.98%
Crinetics Pharmaceuticals Inc.
CRNX
US22663K1079
43770
1.85%
ACADIA Pharmaceuticals Inc.
ACAD
US0042251084
74317
1.82%
Akero Therapeutics Inc.
AKRO
US00973Y1082
34543
1.78%
Celcuity Inc.
CELC
US15102K1007
18484
1.75%
Newamsterdam Pharma Co. NV
NAMS
NL00150012L7
51036
1.73%
Praxis Precision Medicines Inc.
PRAX
US74006W2070
9656
1.73%
Viking Therapeutics Inc.
VKTX
US92686J1060
50644
1.63%
Arcellx Inc.
ACLX
US03940C1009
23254
1.56%
Tarsus Pharmaceuticals Inc.
TARS
US87650L1035
19829
1.52%
Mirum Pharmaceuticals Inc.
MIRM
US6047491013
22211
1.49%
Apogee Therapeutics Inc.
APGE
US03770N1019
20762
1.47%
Xenon Pharmaceuticals Inc.
XENE
CA98420N1050
34396
1.46%
Travere Therapeutics Inc.
TVTX
US89422G1076
43606
1.42%
CG oncology Inc.
CGON
US1569441009
34678
1.38%
Disc Medicine Inc.
IRON
US2546041011
15503
1.29%
Amicus Therapeutics Inc.
FOLD
US03152W1099
136740
1.28%
Ideaya Biosciences Inc.
IDYA
US45166A1025
38786
1.23%
Nuvation Bio Inc.
NUVB
US67080N1019
152082
1.20%
Arcus Biosciences Inc.
RCUS
US03969F1093
48578
1.19%
Apellis Pharmaceuticals Inc.
APLS
US03753U1060
58034
1.18%
Denali Therapeutics Inc.
DNLI
US24823R1059
64726
1.13%
Vera Therapeutics Inc.
VERA
US92337R1014
28383
1.11%
Viridian Therapeutics Inc.
VRDN
US92790C1045
36840
1.06%
Edgewise Therapeutics Inc.
EWTX
US28036F1057
47245
1.04%
Terns Pharmaceuticals Inc.
TERN
US8808811074
39417
0.92%
Zai Lab Ltd.
ZLAB
US98887Q1040
48584
0.90%
Galapagos NV
GLPG
US36315X1019
29514
0.82%
Immunocore Holdings PLC
IMCR
US45258D1054
22504
0.81%
Aurinia Pharmaceuticals Inc.
AUPH
CA05156V1022
56371
0.80%
Pharvaris NV
PHVS
NL00150005Y4
28380
0.79%
Celldex Therapeutics Inc.
CLDX
US15117B2025
29518
0.79%
Olema Pharmaceuticals Inc.
OLMA
US68062P1066
30038
0.79%
Structure Therapeutics Inc.
GPCR
US86366E1064
25792
0.76%
MannKind Corp.
MNKD
US56400P7069
141314
0.76%
Vericel Corp.
VCEL
US92346J1088
21069
0.71%
Trevi Therapeutics Inc.
TRVI
US89532M1018
53817
0.71%
BioCryst Pharmaceuticals Inc.
BCRX
US09058V1035
93421
0.69%
Stoke Therapeutics Inc.
STOK
US86150R1077
23269
0.68%
Immunome Inc.
IMNM
US45257U1088
36238
0.67%
Agios Pharmaceuticals Inc.
AGIO
US00847X1046
25453
0.65%
Zenas Biopharma Inc.
ZBIO
US98937L1052
18476
0.62%
Upstream Bio Inc.
UPB
US91678A1079
24027
0.61%
Dianthus Therapeutics Inc.
DNTH
US2528281080
14474
0.57%
Relay Therapeutics Inc.
RLAY
US75943R1023
75919
0.57%
Capricor Therapeutics Inc.
CAPR
US14070B3096
19645
0.53%
Immatics NV
IMTX
NL0015285941
53445
0.52%
Xencor Inc.
XNCR
US98401F1057
31389
0.52%
AnaptysBio Inc.
ANAB
US0327241065
12334
0.51%
MBX Biosciences Inc.
MBX
US55287L1017
15540
0.51%
Maze Therapeutics Inc.
MAZE
US5787841007
12697
0.48%
UroGen Pharma Ltd.
URGN
IL0011407140
20632
0.48%
Tyra Biosciences Inc.
TYRA
US90240B1061
22820
0.46%
Novavax Inc.
NVAX
US6700024010
69812
0.45%
Palvella Therapeutics Inc.
PVLA
US6979471090
5064
0.43%
Bicara Therapeutics Inc.
BCAX
US0554771032
24399
0.42%
Rapport Therapeutics Inc.
RAPP
US75383L1026
15769
0.42%
ARS Pharmaceuticals Inc.
SPRY
US82835W1080
45490
0.42%
Kura Oncology Inc.
KURA
US50127T1097
35992
0.41%
Theravance Biopharma Inc.
TBPH
KYG8807B1068
22478
0.39%
Compass Therapeutics Inc.
CMPX
US20454B1044
76438
0.39%
Erasca Inc.
ERAS
US29479A1088
121752
0.37%
Vir Biotechnology Inc.
VIR
US92764N1028
61052
0.37%
Fulgent Genetics Inc.
FLGT
US3596641098
13395
0.37%
MoonLake Immunotherapeutics
MLTX
KY61559X1045
28389
0.36%
Rezolute Inc.
RZLT
US76200L3096
39450
0.36%
Day One Biopharmaceuticals Inc.
DAWN
US23954D1090
44903
0.35%
Rigel Pharmaceuticals Inc.
RIGL
US7665597024
7738
0.35%
Replimune Group Inc.
REPL
US76029N1063
34830
0.34%
Geron Corp.
GERN
US3741631036
279271
0.32%
Keros Therapeutics Inc.
KROS
US4923271013
18062
0.31%
Astria Therapeutics Inc.
ATXS
US04635X1028
24204
0.30%
Gossamer Bio Inc.
GOSS
US38341P1021
90858
0.28%
REGENXBIO Inc.
RGNX
US75901B1070
22838
0.26%
Prothena Corp. PLC
PRTA
IE00B91XRN20
23727
0.20%
Compass Pathways PLC
CMPS
US20451W1018
41447
0.18%
Annexon Inc.
ANNX
US03589W1027
43983
0.18%
Akebia Therapeutics Inc.
AKBA
US00972D1054
116038
0.16%
Autolus Therapeutics PLC
AUTL
US05280R1005
114538
0.16%
Anavex Life Sciences Corp.
AVXL
US0327973006
35659
0.15%
Bicycle Therapeutics PLC
BCYC
US0887861088
22302
0.14%
Delcath Systems Inc.
DCTH
US24661P8077
15563
0.13%
Vanda Pharmaceuticals Inc.
VNDA
US9216591084
24780
0.12%
Candel Therapeutics Inc.
CADL
US1374041093
24110
0.10%
Atea Pharmaceuticals Inc.
AVIR
US04683R1068
32596
0.08%
Arcturus Therapeutics Holdings Inc.
ARCT
US03969T1097
11814
0.06%
Tonix Pharmaceuticals Holding Corp.
TNXP
US8902608392
3253
0.01%
Cash and Equivalents
21443.51
0.00%
AstraZeneca PLC
2334482D
36586
0.00%
Radius Health CVR
RAD-CVR
28640
0.00%
Chinook Therapeutics Inc.
1835589D
20700