Companies: 10,636     total market cap: $135.245 T
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iShares Biotechnology ETF
IBB
#274
ETF rank
$8.62 B
Marketcap
๐Ÿ‡บ๐Ÿ‡ธ US
Market
$172.11
Share price
-0.07%
Change (1 day)
22.33%
Change (1 year)
๐Ÿงฌ Biotech ETFs
Categories
iShares Biotechnology ETF (IBB) seeks to track the performance of the NYSE Biotechnology Index, providing exposure to U.S.-listed companies in the biotechnology sector. The fund offers targeted access to biotech stocks, allowing investors to express a view on the industry.

iShares Biotechnology ETF - Holdings

Etf holdings as of December 3, 2025

Number of holdings: 247

Full holdings list

Weight %NameTickerShares Held
7.72%AMGEN INCAMGN1926893.00
7.61%VERTEX PHARMACEUTICALS INCVRTX1417794.00
7.11%GILEAD SCIENCES INCGILD4907407.00
6.16%REGENERON PHARMACEUTICALS INCREGN734839.00
4.95%ALNYLAM PHARMACEUTICALS INCALNY903131.00
3.56%INSMED INCINSM1487300.00
3.31%ARGENX SE ADRARGX309522.00
3.19%IQVIA HOLDINGS INCIQV1212572.00
2.63%NATERA INCNTRA951945.00
2.45%METTLER TOLEDO INCMTD147151.00
2.21%BIOGEN INCBIIB1052924.00
1.97%WATERS CORPWAT427355.00
1.76%BEONE MEDICINES AGONC448237.00
1.75%UNITED THERAPEUTICS CORPUTHR314771.00
1.63%INCYTE CORPINCY1388187.00
1.59%ILLUMINA INCILMN1075126.00
1.22%NEUROCRINE BIOSCIENCES INCNBIX694244.00
1.20%GENMAB SPONSORED ADRGMAB3257882.00
1.09%MEDPACE HOLDINGS INCMEDP163242.00
1.08%IONIS PHARMACEUTICALS INCIONS1137369.00
1.05%REVOLUTION MEDICINES INCRVMD1165656.00
1.00%BRIDGEBIO PHARMA INCBBIO1166602.00
0.98%MADRIGAL PHARMACEUTICALS INCMDGL145070.00
0.96%EXELIXIS INCEXEL1875117.00
0.86%BIOMARIN PHARMACEUTICAL INCBMRN1360509.00
0.82%BIO TECHNE CORPTECH1107195.00
0.78%AVIDITY BIOSCIENCES INCRNA946032.00
0.75%CHARLES RIVER LABORATORIES INTERNACRL349963.00
0.74%ROIVANT SCIENCES LTDROIV3092427.00
0.74%REPLIGEN CORPRGEN382473.00
0.72%MODERNA INCMRNA2470621.00
0.72%ASCENDIS PHARMA ADR REPRESENTINGASND307683.00
0.70%ARROWHEAD PHARMACEUTICALS INCARWR924019.00
0.63%CYTOKINETICS INCCYTK842695.00
0.62%HALOZYME THERAPEUTICS INCHALO831803.00
0.60%TEMPUS AI INC CLASS ATEM691534.00
0.55%MERUS NVMRUS490948.00
0.54%RHYTHM PHARMACEUTICALS INCRYTM442955.00
0.51%BIONTECH SE ADRBNTX455449.00
0.51%AXSOME THERAPEUTICS INCAXSM295760.00
0.50%VAXCYTE INCPCVX903394.00
0.48%PTC THERAPEUTICS INCPTCT547543.00
0.45%KRYSTAL BIOTECH INCKRYS178984.00
0.42%PROTAGONIST THERAPEUTICS INCPTGX423120.00
0.41%BRUKER CORPBRKR740958.00
0.40%CRISPR THERAPEUTICS AGCRSP621253.00
0.40%NUVALENT INC CLASS ANUVL321537.00
0.40%ALKERMESALKS1156722.00
0.38%ADMA BIOLOGICS INCADMA1657923.00
0.37%COGENT BIOSCIENCES INCCOGT810497.00
0.36%ACADIA PHARMACEUTICALS INCACAD1204191.00
0.35%PRAXIS PRECISION MEDICINES INCPRAX163836.00
0.34%CRINETICS PHARMACEUTICALS INCCRNX626529.00
0.32%KYMERA THERAPEUTICS INCKYMR423410.00
0.32%AKERO THERAPEUTICS INCAKRO508349.00
0.31%VERACYTE INCVCYT552612.00
0.30%LEGEND BIOTECH ADR REP CORPLEGN917433.00
0.28%APOGEE THERAPEUTICS INCAPGE327378.00
0.27%ULTRAGENYX PHARMACEUTICAL INCRARE646563.00
0.27%XENON PHARMACEUTICALS INCXENE531964.00
0.27%SCHOLAR ROCK HOLDING CORPSRRK534422.00
0.26%TARSUS PHARMACEUTICALS INCTARS277141.00
0.26%ARCUTIS BIOTHERAPEUTICS INCARQT751052.00
0.25%TRAVERE THERAPEUTICS INCTVTX623595.00
0.25%GRAIL INCGRAL214652.00
0.25%ARCELLX INCACLX297399.00
0.25%AMICUS THERAPEUTICS INCFOLD2169194.00
0.24%MIRUM PHARMACEUTICALS INCMIRM292043.00
0.23%IDEAYA BIOSCIENCES INCIDYA579360.00
0.22%NEWAMSTERDAM PHARMA NVNAMS525273.00
0.21%ADAPTIVE BIOTECHNOLOGIES CORPADPT1043455.00
0.20%BEAM THERAPEUTICS INCBEAM658309.00
0.20%DENALI THERAPEUTICS INCDNLI912776.00
0.19%APELLIS PHARMACEUTICALS INCAPLS752288.00
0.18%SPYRE THERAPEUTICS INCSYRE493365.00
0.18%DYNE THERAPEUTICS INCDYN788115.00
0.18%DISC MEDICINE INCIRON165094.00
0.17%SUMMIT THERAPEUTICS INCSMMT808896.00
0.17%SAREPTA THERAPEUTICS INCSRPT670300.00
0.17%VERA THERAPEUTICS INC CLASS AVERA350854.00
0.17%CG ONCOLOGY INCCGON338793.00
0.17%MINERALYS THERAPEUTICS INCMLYS363944.00
0.16%10X GENOMICS INC CLASS ATXG794471.00
0.16%RECURSION PHARMACEUTICALS INC CLASRXRX2989030.00
0.16%NUVATION BIO INC CLASS ANUVB1656470.00
0.16%ARCUS BIOSCIENCES INCRCUS539495.00
0.16%TERNS PHARMACEUTICALS INCTERN501089.00
0.16%ZYMEWORKS INCZYME524827.00
0.16%VERICEL CORPVCEL360653.00
0.15%TWIST BIOSCIENCE CORPTWST415818.00
0.15%AURINIA PHARMACEUTICALS INCAUPH859103.00
0.15%CENTESSA PHARMACEUTICALS AMERICANCNTA435209.00
0.15%EDGEWISE THERAPEUTICS INCEWTX539924.00
0.14%NURIX THERAPEUTICS INCNRIX718981.00
0.14%MANNKIND CORPMNKD2153672.00
0.14%SYNDAX PHARMACEUTICALS INCSNDX603044.00
0.13%IMMUNOVANT INCIMVT507386.00
0.13%BIOCRYST PHARMACEUTICALS INCBCRX1465598.00
0.13%ZAI LABORATORY ADR REPRESENTING LTZLAB557105.00
0.13%AGIOS PHARMACEUTICALS INCAGIO392417.00
0.12%OLEMA PHARMACEUTICALS INCOLMA379377.00
0.12%STOKE THERAPEUTICS INCSTOK332271.00
0.12%UNIQURE NVQURE394109.00
0.11%IMMUNOCORE HOLDINGS ADR PLCIMCR255628.00
0.11%FORTREA HOLDINGS INCFTRE655521.00
0.11%DYNAVAX TECHNOLOGIES CORPDVAX844535.00
0.11%STRUCTURE THERAPEUTICS ADR INCGPCR288957.00
0.10%ORUKA THERAPEUTICS INCORKA303531.00
0.10%NOVOCURE LTDNVCR715757.00
0.10%XENCOR INCXNCR481183.00
0.10%STEVANATO GROUPSTVN355288.00
0.09%AMYLYX PHARMACEUTICALS INCAMLX572976.00
0.09%ANAPTYSBIO INCANAB183950.00
0.09%MESOBLAST ADR REPRESENTING LTDMESO472721.00
0.09%GALAPAGOS ADR REPRESENTING NVGLPG251506.00
0.09%CASTLE BIOSCIENCES INCCSTL202326.00
0.09%TREVI THERAPEUTICS INCTRVI579946.00
0.09%USD CASHUSD7882855.00
0.09%GRIFOLS ADR REPRESENTING ONE NON-VGRFS878921.00
0.09%RELAY THERAPEUTICS INCRLAY945294.00
0.08%NOVAVAX INCNVAX1070995.00
0.08%KURA ONCOLOGY INCKURA604303.00
0.08%TAYSHA GENE THERAPIES INCTSHA1606226.00
0.08%UROGEN PHARMA LTDURGN283922.00
0.08%CAREDX INCCDNA356467.00
0.08%JANUX THERAPEUTICS INCJANX388890.00
0.08%INTELLIA THERAPEUTICS INCNTLA729367.00
0.08%WAVE LIFE SCIENCES LTDWVE912088.00
0.07%THERAVANCE BIOPHARMA INCTBPH332454.00
0.07%BIOHAVEN LTDBHVN667541.00
0.07%TANGO THERAPEUTICS INCTNGX625198.00
0.07%RIGEL PHARMACEUTICALS INCRIGL125283.00
0.07%INHIBRX BIOSCIENCES INCINBX70880.00
0.07%ENLIVEN THERAPEUTICS INCELVN277394.00
0.07%ABCELLERA BIOLOGICS INCABCL1632439.00
0.07%RAPPORT THERAPEUTICS INCRAPP202475.00
0.06%BLK CSH FND TREASURY SL AGENCYXTSLA5572623.00
0.06%GERON CORPGERN4339590.00
0.06%TYRA BIOSCIENCES INCTYRA245206.00
0.06%EVOTEC SE SPONSORED ADREVO1611013.00
0.06%ARVINAS INCARVN398077.00
0.06%CORMEDIX INCCRMD480203.00
0.06%LENZ THERAPEUTICS INCLENZ174230.00
0.06%IMMUNITYBIO INCIBRX2185675.00
0.05%REPLIMUNE GROUP INCREPL459566.00
0.05%ARBUTUS BIOPHARMA CORPABUS1068361.00
0.05%MYRIAD GENETICS INCMYGN634377.00
0.05%IOVANCE BIOTHERAPEUTICS INCIOVA2101825.00
0.05%SANA BIOTECHNOLOGY INCSANA1038169.00
0.05%PACIFIC BIOSCIENCES OF CALIFORNIAPACB1898137.00
0.05%DAY ONE BIOPHARMACEUTICALS INCDAWN535852.00
0.05%CYTEK BIOSCIENCES INCCTKB829378.00
0.05%MONTE ROSA THERAPEUTICS INCGLUE263582.00
0.05%ORIC PHARMACEUTICALS INCORIC401411.00
0.05%ASTRIA THERAPEUTICS INCATXS325001.00
0.05%EMERGENT BIOSOLUTIONS INCEBS366504.00
0.05%ARRIVENT BIOPHARMA INCAVBP185160.00
0.05%REGENXBIO INCRGNX328629.00
0.05%IRONWOOD PHARMA INC CLASS AIRWD1122395.00
0.05%VIR BIOTECHNOLOGY INCVIR643175.00
0.05%FULGENT GENETICS INCFLGT141585.00
0.05%ARS PHARMACEUTICALS INCSPRY420950.00
0.05%PHATHOM PHARMACEUTICALS INCPHAT272813.00
0.05%KALVISTA PHARMACEUTICALS INCKALV268796.00
0.04%PERSONALIS INCPSNL380031.00
0.04%ANNEXON INCANNX893546.00
0.04%ERASCA INCERAS1155113.00
0.04%PRECIGEN INCPGEN1059945.00
0.04%STANDARD BIOTOOLS INCLAB2623937.00
0.04%KEROS THERAPEUTICS INCKROS208614.00
0.04%ALUMIS INCALMS479607.00
0.04%LEXEO THERAPEUTICS INCLXEO434240.00
0.04%SAVARA INCSVRA582141.00
0.04%ALVOTECH SAALVO782420.00
0.04%CUREVAC NVCVAC685524.00
0.04%OPKO HEALTH INCOPK2571878.00
0.04%PROTHENA PLCPRTA311535.00
0.04%ZEVRA THERAPEUTICS INCZVRA398407.00
0.04%CORVUS PHARMACEUTICALS INCCRVS397572.00
0.04%4D MOLECULAR THERAPEUTICS INCFDMT309346.00
0.04%ALTIMMUNE INCALT631888.00
0.04%MEIRAGTX HOLDINGS PLCMGTX388777.00
0.04%ABSCI CORPABSI938175.00
0.03%CULLINAN THERAPEUTICS INCCGEM265846.00
0.03%ENANTA PHARMACEUTICALS INCENTA194502.00
0.03%ANAVEX LIFE SCIENCES CORPAVXL596151.00
0.03%GINKGO BIOWORKS HOLDINGS INC CLASSDNA290789.00
0.03%MARAVAI LIFESCIENCES HOLDINGS INCMRVI742118.00
0.03%ADC THERAPEUTICS SAADCT633038.00
0.03%PRIME MEDICINE INCPRME677693.00
0.03%PEPGEN INCPEPG456249.00
0.03%ROCKET PHARMACEUTICALS INCRCKT709735.00
0.03%COMPASS PATHWAYS ADR PLCCMPS459092.00
0.03%SOLID BIOSCIENCES INCSLDB421197.00
0.03%DESIGN THERAPEUTICS INCDSGN223576.00
0.02%QUANTERIX CORPQTRX281766.00
0.02%VANDA PHARMACEUTICALS INCVNDA394936.00
0.02%CYBIN INCCYBN334620.00
0.02%AURA BIOSCIENCES INCAURA298280.00
0.02%AUTOLUS THERAPEUTICS ADR PLCAUTL1218059.00
0.02%NEUROGENE INCNGNE87002.00
0.02%ALLOGENE THERAPEUTICS INCALLO1112605.00
0.02%ENTRADA THERAPEUTICS INCTRDA165601.00
0.02%BICYCLE THERAPEUTICS ADR PLCBCYC223435.00
0.02%EDITAS MEDICINE INCEDIT642582.00
0.02%TECTONIC THERAPEUTIC INCTECX74945.00
0.02%C4 THERAPEUTICS INCCCCC518868.00
0.02%PYXIS ONCOLOGY INCPYXS310794.00
0.02%ATEA PHARMACEUTICALS INCAVIR461655.00
0.02%VOYAGER THERAPEUTICS INCVYGR321515.00
0.02%HUMACYTE INCHUMA1044018.00
0.01%IMMUTEP ADS REPRESENTING LTDIMMP760547.00
0.01%AC IMMUNE SAACIU437257.00
0.01%LARIMAR THERAPEUTICS INCLRMR348955.00
0.01%ARCTURUS THERAPEUTICS HOLDINGS INCARCT178458.00
0.01%KYVERNA THERAPEUTICS INCKYTX156696.00
0.01%LYELL IMMUNOPHARMA INCLYEL49934.00
0.01%MAXCYTE INCMXCT727051.00
0.01%CODEXIS INCCDXS630994.00
0.01%NEUMORA THERAPEUTICS INCNMRA462763.00
0.01%PERSPECTIVE THERAPEUTICS INCCATX436032.00
0.01%FOGHORN THERAPEUTICS INCFHTX200151.00
0.01%CASH COLLATERAL USD SGAFTSGAFT883000.00
0.01%FATE THERAPEUTICS INCFATE797278.00
0.01%MERSANA THERAPEUTICS INCMRSN30128.00
0.01%CLIMB BIO INCCLYM409032.00
0.01%NKARTA INCNKTX388418.00
0.01%ALECTOR INCALEC559278.00
0.01%PLIANT THERAPEUTICS INCPLRX404080.00
0.01%MACROGENICS INCMGNX424509.00
0.01%SUTRO BIOPHARMA INCSTRO59442.00
0.00%CARTESIAN THERAPEUTICS INCRNAC61506.00
0.00%ALPHA TEKNOVA INCTKNO82956.00
0.00%BIOMEA FUSION INCBMEA379362.00
0.00%ACRIVON THERAPEUTICS INCACRV158552.00
0.00%TSCAN THERAPEUTICS INCTCRX330788.00
0.00%ARTIVA BIOTHERAPEUTICS INCARTV83053.00
0.00%SILENCE THERAPEUTICS ADR REPRESENTSLN39697.00
0.00%APPLIED THERAPEUTICS INCAPLT923906.00
0.00%ONKURE THERAPEUTICS INC CLASS AOKUR64513.00
0.00%TEVOGEN BIO HOLDINGS INCTVGN317531.00
0.00%Q32 BIO INCQTTB30406.00
0.00%CHINOOK THERAPEUTICS INCADRO320962.00
0.00%THIRD HARMONIC BIO INCTHRD134478.00
0.00%CARGO THERAPEUTICS INCCRGX198104.00
0.00%RUSSELL 2000 EMINI CME DEC 25RTYZ541.00
0.00%E-MINI HEALTH CARE SECTOR DEC 25IXCZ555.00

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