Companies: 11,336     total market cap: $152.999 T
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iShares Biotechnology ETF
IBB
#281
ETF rank
$10.50 B
Marketcap
๐Ÿ‡บ๐Ÿ‡ธ US
Market
$204.56
Share price
-1.21%
Change (1 day)
42.64%
Change (1 year)
๐Ÿงฌ Biotech ETFs
Categories
iShares Biotechnology ETF (IBB) seeks to track the performance of the NYSE Biotechnology Index, providing exposure to U.S.-listed companies in the biotechnology sector. The fund offers targeted access to biotech stocks, allowing investors to express a view on the industry.

iShares Biotechnology ETF - Holdings

Etf holdings as of September 17, 2026Number of holdings: 243

Full holdings list

Weight %NameTickerShares Held
7.80%
VERTEX PHARMACEUTICALSVRTX1597506.00
7.62%
AMGEN INCAMGN2122822.00
7.59%
GILEAD SCIENCESGILD5318354.00
5.77%
REGENERON PHARMACEUTICALSREGN772717.00
4.16%
MODERNAMRNA2782310.00
3.75%
ARGENX SE ADRARGX397871.00
3.62%
NATERANTRA1045710.00
2.71%
REVOLUTION MEDICINESRVMD1457905.00
2.68%
ILLUMINA INCILMN1155578.00
2.36%
ALNYLAM PHARMACEUTICALSALNY1018132.00
2.32%
BIOGENBIIB1120795.00
2.04%
BEONE MEDICINES AGONC609674.00
1.93%
INSMEDINSM1643991.00
1.83%
INCYTE CORPINCY1515732.00
1.49%
ROIVANT SCIENCES LTDROIV3953720.00
1.48%
UNITED THERAPEUTICSUTHR314256.00
1.31%
GENMAB SPONSORED ADRGMAB3999531.00
1.09%
NEUROCRINE BIOSCIENCESNBIX756503.00
1.07%
ASCENDIS PHARMAASND473473.00
1.03%
EXELIXIS INCEXEL1865216.00
1.02%
MEDPACE HOLDINGSMEDP176187.00
0.97%
CHARLES RIVER LABORATORIES INTERNACRL364455.00
0.93%
HALOZYME THERAPEUTICSHALO898950.00
0.90%
BIOMARIN PHARMACEUTICALBMRN1457351.00
0.84%
MADRIGAL PHARMACEUTICALSMDGL166130.00
0.82%
BRIDGEBIO PHARMABBIO1294669.00
0.82%
BIO TECHNETECH1194574.00
0.69%
REPLIGENRGEN408136.00
0.68%
CYTOKINETICSCYTK1022307.00
0.67%
TWIST BIOSCIENCETWST456655.00
0.67%
AXSOME THERAPEUTICSAXSM329351.00
0.65%
BIONTECH SE ADRBNTX699478.00
0.65%
ARROWHEAD PHARMACEUTICALSARWR1013301.00
0.63%
PROTAGONIST THERAPEUTICSPTGX467392.00
0.63%
KRYSTAL BIOTECHKRYS197046.00
0.63%
10X GENOMICS CLASS ATXG862721.00
0.62%
VAXCYTEPCVX1081557.00
0.62%
TEMPUS AI CLASS ATEM809694.00
0.61%
KYMERA THERAPEUTICSKYMR544975.00
0.59%
PRAXIS PRECISION MEDICINESPRAX199981.00
0.55%
ALKERMESALKS1248877.00
0.55%
IONIS PHARMACEUTICALSIONS1241439.00
0.52%
SPYRE THERAPEUTICS INCSYRE592327.00
0.51%
BRUKERBRKR851833.00
0.50%
ABIVAX AMERICAN DEPOSITARY SHARESABVX495204.00
0.48%
RHYTHM PHARMACEUTICALSRYTM508655.00
0.42%
TRAVERE THERAPEUTICSTVTX692732.00
0.40%
PTC THERAPEUTICSPTCT614470.00
0.38%
XENON PHARMACEUTICALSXENE695704.00
0.37%
CRISPR THERAPEUTICS AGCRSP686912.00
0.36%
ORUKA THERAPEUTICS INCORKA388221.00
0.36%
DEFINIUM THERAPEUTICS INCDFTX976728.00
0.36%
MIRUM PHARMACEUTICALSMIRM380382.00
0.35%
COGENT BIOSCIENCESCOGT1128172.00
0.34%
SCHOLAR ROCK HOLDINGSRRK739216.00
0.34%
ACADIA PHARMACEUTICALSACAD1296453.00
0.32%
ADAPTIVE BIOTECHNOLOGIESADPT1181519.00
0.31%
CG ONCOLOGYCGON439676.00
0.28%
IOVANCE BIOTHERAPEUTICS INCIOVA2967332.00
0.27%
CARIS LIFE SCIENCESCAI936905.00
0.27%
ERASCAERAS1884771.00
0.27%
EDGEWISE THERAPEUTICSEWTX600182.00
0.26%
AMYLYX PHARMACEUTICALSAMLX812472.00
0.23%
IDEAYA BIOSCIENCESIDYA635425.00
0.23%
TARSUS PHARMACEUTICALSTARS308754.00
0.23%
IMMUNITYBIOIBRX2876891.00
0.23%
GRAIL INCGRAL303126.00
0.23%
VERACYTEVCYT594417.00
0.23%
RELAY THERAPEUTICSRLAY1253580.00
0.22%
IMMUNOVANTIMVT619249.00
0.22%
DENALI THERAPEUTICSDNLI1137822.00
0.22%
ABCELLERA BIOLOGICSABCL1795683.00
0.21%
ARCUTIS BIOTHERAPEUTICSARQT844639.00
0.21%
UNIQUREQURE493042.00
0.20%
TANGO THERAPEUTICSTNGX912714.00
0.20%
ENLIVEN THERAPEUTICSELVN424258.00
0.20%
DYNE THERAPEUTICSDYN1144757.00
0.19%
LEGEND BIOTECH ADR REPLEGN1134740.00
0.18%
CAREDXCDNA356883.00
0.18%
NURIX THERAPEUTICSNRIX751022.00
0.17%
SUMMIT THERAPEUTICSSMMT1029535.00
0.17%
ZAI LABORATORY ADR REPRESENTING LTZLAB686021.00
0.17%
BEAM THERAPEUTICSBEAM717144.00
0.16%
BLK CSH FND TREASURY SL AGENCYXTSLA17421536.00
0.15%
ARCUS BIOSCIENCESRCUS640964.00
0.15%
SAREPTA THERAPEUTICSSRPT774246.00
0.15%
STRUCTURE THERAPEUTICS ADRGPCR447031.00
0.15%
VERICELVCEL387663.00
0.15%
ADMA BIOLOGICSADMA1730093.00
0.15%
VERA THERAPEUTICS CLASS AVERA448332.00
0.14%
ZYMEWORKSZYME538798.00
0.14%
AURINIA PHARMACEUTICALSAUPH869572.00
0.14%
DISC MEDICINEIRON212256.00
0.14%
FORTREA HOLDINGS INCFTRE720631.00
0.14%
KODIAK SCIENCESKOD444337.00
0.14%
MBX BIOSCIENCESMBX225563.00
0.14%
BIOCRYST PHARMACEUTICALSBCRX1654379.00
0.14%
AGIOS PHARMACEUTICALSAGIO426136.00
0.13%
NEWAMSTERDAM PHARMANAMS613908.00
0.13%
NOVOCURENVCR797547.00
0.13%
BIOHAVENBHVN959374.00
0.12%
XENCORXNCR536411.00
0.12%
MINERALYS THERAPEUTICSMLYS464441.00
0.12%
UROGEN PHARMAURGN293335.00
0.12%
RECURSION PHARMACEUTICALS CLASS ARXRX3595756.00
0.12%
COMPASS PATHWAYS ADR PLCCMPS832841.00
0.12%
GRIFOLS ADR REPRESENTING ONE NON-VGRFS1686545.00
0.12%
INTELLIA THERAPEUTICSNTLA1011967.00
0.11%
NOVAVAXNVAX1196767.00
0.11%
NUVATION BIO CLASS ANUVB1894984.00
0.11%
ANAPTYSBIOANAB208557.00
0.11%
VIR BIOTECHNOLOGYVIR1023222.00
0.10%
STOKE THERAPEUTICSSTOK377391.00
0.10%
SYNDAX PHARMACEUTICALSSNDX615811.00
0.10%
GH RESEARCH PLCGHRS377105.00
0.10%
TREVI THERAPEUTICSTRVI709275.00
0.10%
IMMUNOCORE HOLDINGS ADR PLCIMCR325313.00
0.10%
TAYSHA GENE THERAPIESTSHA2034156.00
0.10%
ABSCI CORPABSI1130161.00
0.09%
ULTRAGENYX PHARMACEUTICALRARE689167.00
0.09%
PRECIGENPGEN1208191.00
0.09%
LAKEFRONT BIOTHERAPEUTICS ADR NVLKFT315781.00
0.09%
RAPPORT THERAPEUTICSRAPP216703.00
0.08%
INHIBRX BIOSCIENCES INCINBX82904.00
0.08%
STEVANATO GROUPSTVN381326.00
0.08%
REPLIMUNE GROUPREPL668445.00
0.08%
PHARVARIS N VPHVS224477.00
0.08%
ALTO NEUROSCIENCE INCANRO270073.00
0.08%
CASTLE BIOSCIENCESCSTL226564.00
0.08%
TYRA BIOSCIENCESTYRA340291.00
0.08%
SEPTERNASEPN208974.00
0.08%
MANNKINDMNKD2269348.00
0.08%
MESOBLAST ADR REPRESENTINGMESO534420.00
0.07%
ZENAS BIOPHARMAZBIO242976.00
0.07%
KURA ONCOLOGYKURA655974.00
0.07%
PERSONALISPSNL473250.00
0.07%
CULLINAN THERAPEUTICSCGEM345752.00
0.07%
JANUX THERAPEUTICSJANX436751.00
0.07%
ARRIVENT BIOPHARMAAVBP249105.00
0.07%
MEIRAGTX HOLDINGS PLCMGTX536067.00
0.06%
BICARA THERAPEUTICS INCBCAX286445.00
0.06%
GERONGERN4792994.00
0.06%
THERAVANCE BIOPHARMATBPH369886.00
0.06%
RIGEL PHARMACEUTICALSRIGL136939.00
0.06%
MAZE THERAPEUTICSMAZE262782.00
0.06%
ARBUTUS BIOPHARMA CORPABUS1203488.00
0.06%
CORVUS PHARMACEUTICALSCRVS482796.00
0.06%
ORIC PHARMACEUTICALSORIC469158.00
0.06%
MARAVAI LIFESCIENCES HOLDINGS INCMRVI805931.00
0.05%
ALVOTECH SAALVO1065436.00
0.05%
MONTE ROSA THERAPEUTICSGLUE447172.00
0.05%
WAVE LIFE SCIENCES INCWVE1219984.00
0.05%
OLEMA PHARMACEUTICALSOLMA542564.00
0.05%
SOLID BIOSCIENCES INCSLDB599321.00
0.05%
ZEVRA THERAPEUTICS INCZVRA448393.00
0.05%
4D MOLECULAR THERAPEUTICS INCFDMT358791.00
0.05%
ANNEXONANNX1240983.00
0.05%
IRONWOOD PHARMA CLASS AIRWD1216919.00
0.05%
CANDEL THERAPEUTICS INCCADL446799.00
0.05%
SAGIMET BIOSCIENCES SERIES ASGMT451393.00
0.05%
ALUMISALMS644091.00
0.04%
CYTEK BIOSCIENCESCTKB913126.00
0.04%
OPKO HEALTHOPK2906297.00
0.04%
ALTIMMUNE INCALT1417538.00
0.04%
ACLARIS THERAPEUTICSACRS849367.00
0.04%
SAVARASVRA823837.00
0.04%
SANA BIOTECHNOLOGYSANA1391096.00
0.04%
OMNIAB INCOABI905807.00
0.04%
NEUROGENENGNE120243.00
0.04%
DESIGN THERAPEUTICSDSGN291062.00
0.03%
REGENXBIORGNX446243.00
0.03%
CYTOMX THERAPEUTICSCTMX1288359.00
0.03%
ARVINASARVN421247.00
0.03%
ARCTURUS THERAPEUTICS HOLDINGS INCARCT203099.00
0.03%
ALLOGENE THERAPEUTICSALLO1981429.00
0.03%
PHATHOM PHARMACEUTICALSPHAT440135.00
0.03%
SILENCE THERAPEUTICS ADR REPRESENTSLN266030.00
0.03%
AURA BIOSCIENCESAURA501765.00
0.03%
PACIFIC BIOSCIENCES OF CALIFORNIAPACB2196654.00
0.03%
FULGENT GENETICSFLGT137693.00
0.03%
EDITAS MEDICINEEDIT1103254.00
0.03%
GINKGO BIOWORKS HOLDINGS CLASS ADNA380476.00
0.03%
CONTINEUM THERAPEUTICS CLASS ACTNM225399.00
0.03%
PROTHENA PLCPRTA351997.00
0.03%
AUTOLUS THERAPEUTICS ADR PLCAUTL1526104.00
0.03%
C4 THERAPEUTICSCCCC847124.00
0.03%
CABALETTA BIOCABA1107143.00
0.03%
ROCKET PHARMACEUTICALSRCKT808185.00
0.03%
MYRIAD GENETICSMYGN666310.00
0.02%
ENANTA PHARMACEUTICALS INCENTA207961.00
0.02%
EMERGENT BIOSOLUTIONSEBS366906.00
0.02%
ATEA PHARMACEUTICALSAVIR487981.00
0.02%
USD CASHUSD2512111.00
0.02%
PRIME MEDICINEPRME715586.00
0.02%
VANDA PHARMACEUTICALS INCVNDA429877.00
0.02%
FULCRUM THERAPEUTICSFULC557054.00
0.02%
STANDARD BIOTOOLSLAB2828940.00
0.02%
KYVERNA THERAPEUTICSKYTX284281.00
0.02%
ARS PHARMACEUTICALSSPRY472145.00
0.02%
PERSPECTIVE THERAPEUTICSCATX679527.00
0.02%
LEXEO THERAPEUTICSLXEO464628.00
0.02%
IMMUNEERING CLASS AIMRX434202.00
0.02%
TECTONIC THERAPEUTICTECX71103.00
0.02%
BIOAGE LABSBIOA238555.00
0.02%
PYXIS ONCOLOGY INCPYXS514776.00
0.02%
BRIDGEBIO ONCOLOGY THERAPEUTICS INBBOT338912.00
0.02%
ANAVEX LIFE SCIENCES CORPAVXL674713.00
0.01%
KEROS THERAPEUTICSKROS137214.00
0.01%
LARIMAR THERAPEUTICSLRMR395737.00
0.01%
CASH COLLATERAL USD SGAFTSGAFT1481000.00
0.01%
LINEAGE CELL THERAPEUTICS INCLCTX1411929.00
0.01%
UPSTREAM BIOUPB273550.00
0.01%
SIONNA THERAPEUTICSSION200411.00
0.01%
PEPGENPEPG478618.00
0.01%
ENTRADA THERAPEUTICSTRDA203651.00
0.01%
AC IMMUNE SA AGACIU462313.00
0.01%
VOYAGER THERAPEUTICSVYGR372065.00
0.01%
TENAYA THERAPEUTICSTNYA1591923.00
0.01%
HUMACYTE INCHUMA1854372.00
0.01%
BICYCLE THERAPEUTICS ADR PLCBCYC281933.00
0.01%
NOVABRIDGE BIOSCIENCES ADRNBP631616.00
0.01%
CODEXISCDXS767794.00
0.01%
FOGHORN THERAPEUTICSFHTX236878.00
0.01%
QUANTUM SI INC CLASS AQSI1279308.00
0.01%
QUANTERIXQTRX299483.00
0.01%
CARIBOU BIOSCIENCESCRBU671368.00
0.01%
LENZ THERAPEUTICSLENZ206143.00
0.01%
ADC THERAPEUTICS SAADCT714442.00
0.01%
BLACK DIAMOND THERAPEUTICS INCBDTX370711.00
0.01%
LYELL IMMUNOPHARMALYEL57776.00
0.01%
ALPHA TEKNOVATKNO82430.00
0.00%
AARDVARK THERAPEUTICSAARD95169.00
0.00%
GOSSAMER BIOGOSS42325.00
0.00%
JYONG BIOTECH LTDMENS219184.00
0.00%
NEUMORA THERAPEUTICS INCNMRA580552.00
0.00%
CELLECTIS ADR REPRESENTING SACLLS238259.00
0.00%
AKERO THERAPEUTICS CVRAKE515954.00
0.00%
IMMUTEP ADS REPRESENTING LTDIMMP783352.00
0.00%
CHINOOK THERAPEUTICS INCADRO320962.00
0.00%
THIRD HARMONIC BIO INCTHRD134478.00
0.00%
CARGO THERAPEUTICS INCCRGX198104.00
0.00%
RUSSELL 2000 EMINI CME DEC 26RTYZ647.00
0.00%
E-MINI HEALTH CARE SECTOR DEC 26IXCZ692.00

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